|
|
linical Infectious Diseases 2007;45:S137-S147
Consumer Antibacterial Soaps: Effective or Just Risky?
Allison E. Aiello,1 Elaine L. Larson,2 and Stuart B. Levy3
1Department of Epidemiology and Center for Social Epidemiology and Population Health, University of Michigan, Ann Arbor; 2School of Nursing, Columbia University, New York, New York; and 3Center for Adaptation Genetics and Drug Resistance, Tufts University School of Medicine, Boston, Massachusetts
Background. Much has been written recently about the potential hazards versus benefits of antibacterial (biocide)–containing soaps. The purpose of this systematic literature review was to assess the studies that have examined the efficacy of products containing triclosan, compared with that of plain soap, in the community setting, as well as to evaluate findings that address potential hazards of this use—namely, the emergence of antibiotic-resistant bacteria.
Methods. The PubMed database was searched for English-language articles, using relevant keyword combinations for articles published between 1980 and 2006. Twenty-seven studies were eventually identified as being relevant to the review.
Results. Soaps containing triclosan within the range of concentrations commonly used in the community setting (0.1%–0.45% wt/vol) were no more effective than plain soap at preventing infectious illness symptoms and reducing bacterial levels on the hands. Several laboratory studies demonstrated evidence of triclosan-adapted cross-resistance to antibiotics among different species of bacteria.
Conclusions. The lack of an additional health benefit associated with the use of triclosan-containing consumer soaps over regular soap, coupled with laboratory data demonstrating a potential risk of selecting for drug resistance, warrants further evaluation by governmental regulators regarding antibacterial product claims and advertising. Further studies of this issue are encouraged.
上一篇:您医院对“医疗废物按照规定的时间和路线运送”是怎样落实的？下一篇:手术室是否每个房间都需要放置利器盒
|
|
发表于 2007-9-29 17:34:00
发表于 2007-9-29 17:34:01
